Article
Molecular monitoring in malaria vaccine trials.
Trends in parasitology - 1 Feb 2003
Felger Ingrid, Genton Blaise, Smith Tom, Tanner Marcel, Beck Hans Peter
Abstract excerpt
Molecular techniques offer new approaches for malaria field trials, particularly PCR techniques, which facilitate accurate diagnosis of Plasmodium infections and increase the power of estimates of vaccine effects on malaria prevalence or incidence. Molecular methods also help to assess selective effects of vaccines. Longitudinal genotyping data can be used to initiate novel analyses of parasite dynamics,...
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