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Article

β-sitosterol, a plant sterol, induces apoptosis and activates key caspases in MDA-MB-231 human breast cancer cells

1 Mar 2003

Abstract excerpt

The objective of the present study was to evaluate the effect of beta-sitosterol, a plant sterol that induces apoptosis in breast cancer cells, on two pathways leading to apoptosis. These pathways are classified based on the localization of the initiated signal, extrinsic and intrinsic pathways. Extrinsic and intrinsic pathways are catalyzed by caspases 8 and 9, respectively, which leads to the activation of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12579296
DOI: 10.3892/or.10.2.497

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