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Osteocalcin gene HindIII C/T polymorphism is a biomarker for prostate cancer and responsiveness to hormone therapy.

European urology - 1 Feb 2003

Wu Hsi-Chin, Lin Cheng-Chieh, Chen Wen-Chi, Chen Huey-Yi, Tsai Fuu-Jen

Abstract excerpt

OBJECTIVES: Osteocalcin is a vitamin-K dependent protein which is related to the metabolism of bone and calcium. The formation or progression of prostate cancer is presumed to be associated with the osteocalcin gene. The most frequently seen polymorphism is HindIII which is located at the promoter region. HindIII is therefore a possible genetic marker in the search for the association between prostate cancer and...

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PMID: 12565780
DOI: 10.1016/s0302-2838(02)00541-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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