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Article

Regulation of capsule synthesis and cell motility in Salmonella enterica by the essential gene igaA.

Genetics - 1 Dec 2002

Cano David A, Domínguez-Bernal Gustavo, Tierrez Alberto, Garcia-Del Portillo Francisco, Casadesús Josep

Abstract excerpt

Mutants of Salmonella enterica carrying the igaA1 allele, selected as able to overgrow within fibroblast cells in culture, are mucoid and show reduced motility. Mucoidy is caused by derepression of wca genes (necessary for capsule synthesis); these genes are regulated by the RcsC/YojN/RcsB phosphorelay system and by the RcsA coregulator. The induction of wca expression in an igaA1 mutant is suppressed by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12524328
DOI: 10.1093/genetics/162.4.1513
PMCID: PMC1462382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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