Article
Genetics of blood pressure, hypertensive complications, and antihypertensive drug responses.
Pharmacogenomics - 1 Jan 2003
Turner Stephen T, Boerwinkle Eric
Abstract excerpt
Hypertension is the most prevalent, treatable risk factor for diseases of the heart, brain and kidneys. In this review, we discuss advances in understanding of the genetics of blood pressure regulation, the development of hypertensive complications and the pharmacodynamics of antihypertensive drug responses. Discovery of single gene mutations that cause hypertension or hypotension in humans suggests that the...
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