Article
The sequential introduction of HIV-1 subtype B and CRF01AE in Singapore by sexual transmission: accelerated V3 region evolution in a subpopulation of Asian CRF01 viruses.
Virology - 20 Dec 2002
Kalish Marcia L, Korber Bette T, Pillai Satish, Robbins Kenneth E, Leo Yee Sin, Saekhou Ae, Verghese Iris, Gerrish Phillip, Goh Chee Leok, Lupo Davis, Tan Boon Huan, Brown Teresa M, Chan Roy
Abstract excerpt
The rapid spread of the human immunodeficiency virus type 1 (HIV-1) circulating recombinant form (CRF) 01AE throughout Asia demonstrates the dynamic nature of emerging epidemics. To further characterize the dissemination of these strains regionally, we sequenced 58 strains from Singapore and found that subtype B and CRF01 were introduced separately, by homosexual and heterosexual transmission, respectively....
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