Article
Whose hypothesis? Ciphering, sectorials, D lesions, freckles and the operation of Stigler's Law.
Cancer biology & therapy - 1 Jan 2000
Kern Scott E
Abstract excerpt
Common references to the famous two-hit hypothesis of tumorigenesis are pervasively erroneous, and the recited tenets of this model vary enormously. Exploration of the history of this model reveals a rich philosophical progression that profited from perceptive observations, clever musings, and rediscoveries by many investigators over a period of decades. The current work is intended to raise the appreciation for...
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