Article
The protective role of the HLA-DR locus in patients with various clinical types of alopecia areata.
Archivum immunologiae et therapiae experimentalis - 1 Jan 2002
Broniarczyk-Dyła Grazyna, Prusińska-Bratoś Magdalena, Dubla-Berner Małgorzata, Arkuszewska Celina, Borowiec Maciej, Kowalski Marek L, Woszczek Grzegorz
Abstract excerpt
One of the genetic factors associated with the development of alopecia areata (AA) is the HLA locus. The study comprised 52 patients with AA aged 10 to 64 years. The frequences of HLA-DRB alleles in the patients and controls were compared. The control group comprised 152 healthy persons. Familial occurrence of AA was seen in 7 (13.5%) cases. A significantly lower frequency of HLA-DRB1*03 was observed in patients...
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