Article
Evidence for the role of demyelination, HLA-DR alleles, and cytokines in the pathogenesis of parvovirus B19 meningoencephalitis and its sequelae.
Journal of neurology, neurosurgery, and psychiatry - 1 Dec 2002
Kerr J R, Barah F, Chiswick M L, McDonnell G V, Smith J, Chapman M D, Bingham J B, Kelleher P, Sheppard M N
Abstract excerpt
OBJECTIVE: To review the clinical and pathological features of parvovirus B19 meningoencephalitis and its sequelae in 12 previously published cases, and to perform additional tests to determine the pathogenesis of the disease. METHODS: Cases were reviewed and available serum and cerebrospinal fluid (CSF) tested for antiganglioside antibodies and a range of cytokines. In situ hybridisation for parvovirus B19 DNA...
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