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Article

Structural model of the transmembrane Fo rotary sector of H+-transporting ATP synthase derived by solution NMR and intersubunit cross-linking in situ.

Biochimica et biophysica acta - 11 Oct 2002

Fillingame Robert H, Dmitriev Oleg Y

Abstract excerpt

H(+)-transporting, F(1)F(o)-type ATP synthases utilize a transmembrane H(+) potential to drive ATP formation by a rotary catalytic mechanism. ATP is formed in alternating beta subunits of the extramembranous F(1) sector of the enzyme, synthesis being driven by rotation of the gamma subunit in the center of the F(1) molecule between the alternating catalytic sites. The H(+) electrochemical potential is thought to...

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PMID: 12409198
DOI: 10.1016/s0005-2736(02)00572-2

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