Genetic diversity of Plasmodium falciparum parasites from Kenya is not affected by antifolate drug selection.

doi:10.1016/s0020-7519(02)00164-9

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Article

Genetic diversity of Plasmodium falciparum parasites from Kenya is not affected by antifolate drug selection.

International journal for parasitology - 1 Nov 2002

Nzila A M, Mberu E K, Nduati E, Ross A, Watkins W M, Sibley C H

Abstract excerpt

The genotypes of merozoite surface protein-1, merozoite surface protein-2 and glutamine rich protein are frequently used to distinguish recrudescence from reinfection when parasitaemia reappears after antimalarial drug treatment. However, none of the previous reports has clearly assessed the change of genetic diversity following drug treatment. In the present study, we have assessed the impact of...

Topics

Age Distribution
Alleles
Animals
Antigens, Protozoan
Antimalarials
Body Temperature
Child, Preschool
Drug Resistance
Fever
Folic Acid Antagonists
Genes, Protozoan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Humans

Infant

Kenya

Malaria

Merozoite Surface Protein 1

Parasitemia

Source

Open in PubMed

Identifiers

PMID: 12392912
DOI: 10.1016/s0020-7519(02)00164-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12392912-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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