Article
[Polymorphism of the tumor necrosis factor alpha gene in patients with infiltrative tuberculosis and from the Bashkorstan populations].
Molekuliarnaia biologiia - 1 Jan 2000
Bikmaeva A R, Sibiriak S V, Valiakhmetova D Kh, Khusnutdinova E K
Abstract excerpt
The polymorphism at position -308 of the TNF-alpha gene promoter was analyzed in three ethnic groups and in patients with infiltrative pulmonary tuberculosis from Bashkortostan. No interethnic difference in allele or genotype frequency distribution was observed. The frequency of allele TNF2 in tuberculosis patients was significantly higher than in controls (chi 2 = 11.69, p = 0.001), suggesting an association of...
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