Article
Evaluation of clinical application of gap-PCR as a routine method for alpha-thalassemia carrier detection.
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA - 1 May 2002
Zhou Yu-Qiu, Xiao Ge-Fei, Li Li-Yan, Li Wen-Dian, Liu Zhong-Ying, Zhu Lan-Fang, Mo Qiu-Hua, Qu Xin-Jun, Xu Xiang-Min
Abstract excerpt
OBJECTIVE: To evaluate the feasibility of using gap-PCR for routine screening of alpha-thalassemia in clinical laboratory. METHODS: A total of 382 clinical blood samples randomly collected from the population of Zhuhai city were screened for alpha-thalassemia determinants with hematological and gap-PCR method respectively in a double-blind manner. Parallel analysis with Southern blotting was performed to verify...
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