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Article

Intrafamilial correlation of clinical manifestations in neurofibromatosis 2 (NF2).

Genetic epidemiology - 1 Oct 2002

Zhao Y, Kumar R A, Baser M E, Evans D G R, Wallace A, Kluwe L, Mautner V F, Parry D M, Rouleau G A, Joe H, Friedman J M

Abstract excerpt

Measuring correlation in clinical traits among relatives is important to our understanding of the causes of variable expressivity in Mendelian diseases. Random effects models are widely used to estimate intrafamilial correlations, but such models have limitations. We incorporated survival techniques into a random effects model so that it can be used to estimate intrafamilial correlations in continuous variables...

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Identifiers

PMID: 12384977
DOI: 10.1002/gepi.10181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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