Article
False negative DNA polymerase chain reaction in an infant with subtype C human immunodeficiency virus type 1 infection
1 Sept 2002
Abstract excerpt
Diagnosis of HIV infection in early infancy generally relies on detection of HIV proviral DNA by PCR. However, many of the HIV DNA PCR assays currently in use either are not optimized or have not been validated for diagnosis of infection with non-subtype B HIV. We report the case of an HIV-infected African immigrant infant with subtype C HIV infection who tested negative repeatedly by HIV DNA PCR. Clinicians...
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