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Early Diagnosis of HIV-1–Infected Infants in Thailand Using RNA and DNA PCR Assays Sensitive to Non-B Subtypes

1 Aug 2000

Abstract excerpt

OBJECTIVES: To evaluate the sensitivity and specificity of RNA and DNA polymerase chain reaction (PCR) for early diagnosis of perinatal HIV-1 infection and to investigate early viral dynamics in infected infants. DESIGN: A cohort study of 395 non-breastfed infants born to HIV-infected mothers in a randomized clinical trial of short-course antenatal zidovudine. METHODS: Infant venous blood specimens collected at...

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PMID: 11035610
DOI: 10.1097/00126334-200008150-00001

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