Article
Monitoring the drug-sensitivity of Plasmodium falciparum in coastal towns in Madagascar by use of in vitro chemosensitivity and mutation detection tests.
Parasite (Paris, France) - 1 Sept 2002
Rason M A, Ariey F, Rafidimanantsoa L, Andrianantenaina B H, Sahondra Harisoa J L, Randrianarivelojosia M
Abstract excerpt
The dissemination of mutant and resistant strains of Plasmodium falciparum makes a considerable contribution to the spread of drug-resistant malaria. Populations around harbours and airports could be particularly exposed to Plasmodium isolates introduced with imported cases of malaria. The use of chloroquine as well as the use of and sulfadoxine/pyrimethamine is currently an effective method for treating...
Topics
- Animals
- Antimalarials
- Chloroquine
- DNA, Protozoan
- Drug Resistance
- Drug Resistance, Multiple
- Drug Therapy, Combination
- Genotype
- Humans
- Madagascar
- Malaria, Falciparum
- Membrane Proteins
- Membrane Transport Proteins