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Growth and molecular evolution of vesicular stomatitis serotype New Jersey in cells derived from its natural insect-host: evidence for natural adaptation.

Virus research - 1 Oct 2002

Llewellyn Z N, Salman M D, Pauszek S, Rodriguez Luis L

Abstract excerpt

In this study we evaluated the growth and molecular evolution of a natural isolate of VSV-NJ (89GAS) from sand flies in cells derived from sand flies (LL5), mosquitoes (C6/36) or hamsters (BHK21). Two VSV-NJ natural isolates of mammalian origin were used for comparison. For each virus we measured: (i) ability to grow in one-step growth curve or after serial passage on each cell type; (ii) ability to induce...

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PMID: 12367751
DOI: 10.1016/s0168-1702(02)00113-2

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