Article
Genetic variation within the premembrane coding region of dengue viruses from the Yucatan peninsula of Mexico.
The American journal of tropical medicine and hygiene - 1 Jul 2002
Díaz Francisco J, Farfán-Ale Jose A, Olson Ken E, Loroño-Pino María A, Gubler Duane J, Blair Carol D, Black William C, Beaty Barry J
Abstract excerpt
Single-strand conformation polymorphism (SSCP) and sequence analyses were used to characterize genetic polymorphisms and phylogenetic relationships, respectively, among dengue (DEN) viruses isolated between 1980 and 1997 from Yucatan, Mexico and surrounding states. Amplified cDNAs from the premembrane (prM) coding region of the DEN viruses were characterized by SSCP. There were six distinct haplotypes of DEN-1...
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