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Article

Conservation of the segmented germband stage: robustness or pleiotropy?

Trends in genetics : TIG - 1 Oct 2002

Galis Frietson, van Dooren Tom J M, Metz Johan A J

Abstract excerpt

Gene expression patterns of the segment polarity genes in the extended and segmented germband stage are remarkably conserved among insects. To explain the conservation of these stages, two hypotheses have been proposed. One hypothesis states that the conservation reflects a high interactivity between modules, so that mutations would have several pleiotropic effects in other parts of the body, resulting in...

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PMID: 12350339
DOI: 10.1016/s0168-9525(02)02739-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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