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Article

5-HT(2A) gene promoter polymorphism as a modifying rather than a vulnerability factor in anorexia nervosa.

European psychiatry : the journal of the Association of European Psychiatrists - 1 Jul 2002

Kipman A, Bruins-Slot L, Boni C, Hanoun N, Adès J, Blot P, Hamon M, Mouren-Siméoni M, Gorwood P

Abstract excerpt

The A allele of the 5-HT(2A) gene (-1438A/G polymorphism) has been associated with anorexia nervosa in four studies, but not in three others. One possibility to explain such a discrepancy is that the A allele acts as a modifying rather than a vulnerability allele. To test this hypothesis, we increased our initial sample of 102 trios left open bracket Mol. Psychiatry 7 (2002) 90 right open bracket with 43 new...

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PMID: 12231269
DOI: 10.1016/s0924-9338(02)00657-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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