Article
The 5-HT(2A) -1438G/A polymorphism in anorexia nervosa: a combined analysis of 316 trios from six European centres.
Molecular psychiatry - 1 Jan 2002
Gorwood P, Adès J, Bellodi L, Cellini E, Collier D A, Di Bella D, Di Bernardo M, Estivill X, Fernandez-Aranda F, Gratacos M, Hebebrand J, Hinney A, Hu X, Karwautz A, Kipman A, Mouren-Siméoni M C, Nacmias B, Ribasés M, Remschmidt H, Ricca V, Rotella C M, Sorbi S, Treasure J
Abstract excerpt
Several case-control association studies have raised the possibility that the A allele of a -1438 G/A polymorphism in the type 2A serotonin receptor (HTR2A) gene may be a risk factor for anorexia nervosa. However the absence of linkage and the existence of negative association studies raise the possibility of false positive findings, resulting from population stratification or lack of statistical power. To...
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