Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular analysis of tyrosine-and phenylalanine-mediated repression of the tyrB promoter by the TyrR protein of Escherichia coli.

Molecular microbiology - 1 Sept 2002

Yang Ji, Camakaris Helen, Pittard James

Abstract excerpt

The mechanism of repression of the tyrB promoter by TyrR protein has been studied in vivo and in vitro. In tyrR+ strains, transcription of tyrB is repressed by either tyrosine or phenylalanine. Both of the TyrR binding sites (strong and weak TyrR boxes) lie downstream of the tyrB transcription start site and are required for tyrosine- or phenylalanine-mediated repression. Our results establish that the binding of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Directed RNA Polymerases
Share to DNA Footprinting

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli Proteins

Share to Genes, Bacterial

Share to Phenylalanine

Share to Regulon

Share to Repressor Proteins

Share to Tyrosine

Source

Identifiers

PMID: 12207706
DOI: 10.1046/j.1365-2958.2002.03108.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular analysis of tyrosine-and phenylalanine-mediated repression of the tyrB promoter by the TyrR protein of Escherichia coli.PMID 12207706Read ↗

Mutations in the tyrR gene of Escherichia coli which affect TyrR-mediated activation but not TyrR-mediated repression.Semantic proximity Read ↗

Activation by TyrR in Escherichia coli K-12 by Interaction between TyrR and the α-Subunit of RNA Polymerase.Semantic proximity Read ↗

Specific contacts between residues in the DNA-binding domain of the TyrR protein and bases in the operator of the tyrP gene of Escherichia coli.Semantic proximity Read ↗

Altered oligomerization properties of N316 mutants of Escherichia coli TyrR.Semantic proximity Read ↗

Amino acid residues in the alpha-subunit C-terminal domain of Escherichia coli RNA polymerase involved in activation of transcription from the mtr promoter.Semantic proximity Read ↗

Repression of the aroP gene of Escherichia coli involves activation of a divergent promoter.Semantic proximity Read ↗

Integration host factor and cyclic AMP receptor protein are required for TyrR-mediated activation of tpl in Citrobacter freundii.Semantic proximity Read ↗

Evidence that regulatory protein MarA of Escherichia coli represses rob by steric hindrance.Semantic proximity Read ↗

The Escherichia coli FIS protein is not required for the activation of tyrT transcription on entry into exponential growth.Semantic proximity Read ↗

tRNA determinants for transcription antitermination of the Bacillus subtilis tyrS gene.Semantic proximity Read ↗

Analysis of the Bacillus subtilis tyrS gene: conservation of a regulatory sequence in multiple tRNA synthetase genes.Semantic proximity Read ↗

Thiobacillus ferrooxidans tyrosyl-tRNA synthetase functions in vivo in Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.