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Article

A novel fibroblast growth factor receptor 2 mutation in Crouzon syndrome associated with Chiari type I malformation and syringomyelia.

Journal of neurosurgery - 1 Aug 2002

Fujisawa Hironori, Hasegawa Mitsuhiro, Kida Shinya, Yamashita Junkoh

Abstract excerpt

OBJECT: It has been reported that due to premature synostosis of the lambdoid suture in the first 24 months of life, more than 70% of patients with Crouzon syndrome concurrently suffer from chronic tonsillar herniation (Chiari Type I malformation) and some (20%) associated syringomyelia. The goal of the present study was to examine mutations in the fibroblast growth factor receptor (FGFR) genes in Crouzon...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Magnetic Resonance Imaging

Share to Polymorphism, Single-Stranded Conformational

Share to Receptor, Fibroblast Growth Factor, Type 2

Share to Receptor Protein-Tyrosine Kinases

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Source

Identifiers

PMID: 12186468
DOI: 10.3171/jns.2002.97.2.0396

Genes

FGFR2
FGFR1
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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