Article
The nucleotide: DNA sequencing and its clinical application.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons - 1 Aug 2002
Kim Yong, Donoff R Bruce, Wong David T W, Todd Randy
Abstract excerpt
Information determining cellular structure and function is contained in chromosomal DNA. Genes, regions of DNA encoding this information, are composed of specific sequences of nucleotides. DNA sequencing methods have been developed to identify these sequences. Even subtle alteration (or mutation) of these sequences can lead to many human syndromes and diseases. This article reviews 1) the structure of the...
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