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Article

Resistance‐associated point mutations of organophosphate insensitive acetylcholinesterase, in the olive fruit fly <i>Bactrocera oleae</i>

25 Jul 2002

Abstract excerpt

A 2.2-kb full length cDNA containing an ORF encoding a putative acetylcholinesterase (AChE) precursor of 673 amino acid residues was obtained by a combined degenerate PCR and RACE strategy from an organophosphate-susceptible Bactrocera oleae strain. A comparison of cDNA sequences of individual insects from susceptible and resistant strains, coupled with an enzyme inhibition assay with omethoate, indicated a novel...

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PMID: 12144698
DOI: 10.1046/j.1365-2583.2002.00343.x

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