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Article

Unraveling the Molecular Pathogenesis of Isolated Proximal Renal Tubular Acidosis

1 Aug 2002

Abstract excerpt

Proximal renal tubular acidosis (pRTA) results from an impairment of bicarbonate (HCO(3)(-)) reabsorption in the renal proximal tubules and is characterized by a decreased renal HCO(3)(-) threshold. Proximal RTA most commonly occurs in association with multiple defects of proximal tubular transport (renal Fanconi syndrome). Although much more rare, pRTA may occur without other functional defects in proximal...

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PMID: 12138151
DOI: 10.1097/01.asn.0000025281.70901.30

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