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Article

Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein

8 Jul 2002

Abstract excerpt

BACKGROUND: The largest open reading frame in the Saccharomyces genome encodes midasin (MDN1p, YLR106p), an AAA ATPase of 560 kDa that is essential for cell viability. Orthologs of midasin have been identified in the genome projects for Drosophila, Arabidopsis, and Schizosaccharomyces pombe. RESULTS: Midasin is present as a single-copy gene encoding a well-conserved protein of approximately 600 kDa in all...

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PMID: 12102729
DOI: 10.1186/1471-2164-3-18

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