Article
Disease surveillance in recombining pathogens: multilocus genotypes identify sources of human Coccidioides infections.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jun 2002
Fisher Matthew C, Rannala Bruce, Chaturvedi Vishnu, Taylor John W
Abstract excerpt
Molecular surveillance of pathogenic microbes works by genotyping isolates with DNA fingerprinting techniques and then using these genotypes to assign individuals to populations. Clonality is assumed in many fingerprinting studies, although this assumption has been shown to be false for many organisms. To accommodate recombining organisms into surveillance programs, methods using population allele frequencies in...
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