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Article

LOS2, a genetic locus required for cold-responsive gene transcription encodes a bi-functional enolase.

The EMBO journal - 3 Jun 2002

Lee Hojoung, Guo Yan, Ohta Masaru, Xiong Liming, Stevenson Becky, Zhu Jian-Kang

Abstract excerpt

The Arabidopsis mutation, los2, impairs cold-responsive gene transcription, acquired freezing tolerance and plant resistance to chilling under certain conditions. LOS2 was isolated through positional cloning and shown to encode an enolase in the glycolytic pathway. In animal cells, enolase has also been known to function as a transcription factor that represses the expression of c-myc by binding to the c-myc gene...

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Identifiers

PMID: 12032082
DOI: 10.1093/emboj/21.11.2692
PMCID: PMC126021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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