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Article

Differentiation and stromal-induced growth promotion of murine prostatic tumors.

The Prostate - 15 May 2002

Salm Sarah N, Takao Tetsuya, Tsujimura Akira, Coetzee Sandra, Moscatelli David, Wilson E Lynette

Abstract excerpt

BACKGROUND: We have derived a panel of p53-null prostatic "basal" and "luminal" epithelial cell lines and their ras transformed counterparts to study stromal/epithelial interactions and the properties of tumors arising from "basal" and "luminal" cells. METHODS: Previously derived normal murine prostatic "basal" epithelial (PE-B-1) and "luminal" epithelial (PE-L-1) cell lines were transformed with N-Ras. These...

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PMID: 11967952
DOI: 10.1002/pros.10075

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