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ColE1-like plasmid pIP843 of Klebsiella pneumoniae encoding extended-spectrum beta-lactamase CTX-M-17.

Antimicrobial agents and chemotherapy - 1 May 2002

Cao Van, Lambert Thierry, Courvalin Patrice

Abstract excerpt

The resistance of Klebsiella pneumoniae BM4493, isolated in Ho Chi Minh City, Vietnam, to cefotaxime and aztreonam was due to production of a novel beta-lactamase, CTX-M-17. The bla(CTX-M-17) gene was borne by 7,086-bp plasmid pIP843, which was entirely sequenced and which was found to belong to the ColE1 family. The 876-bp bla(CTX-M-17) gene differed from bla(CTX-M-14) by 2 nucleotides, which led to the single...

Topics

Anti-Bacterial Agents
Base Sequence
Cefotaxime
Cephalosporins
Conjugation, Genetic
DNA Transposable Elements
Klebsiella pneumoniae
Microbial Sensitivity Tests
Molecular Sequence Data
Mutation
Plasmids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

beta-Lactam Resistance

beta-Lactamases

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Identifiers

PMID: 11959547
DOI: 10.1128/AAC.46.5.1212-1217.2002
PMCID: PMC127148

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