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Article

Construction and characterization of an acapsular mutant of Mannheimia haemolytica A1.

Infection and immunity - 1 May 2002

McKerral Linda J, Lo Reggie Y C

Abstract excerpt

The nmaA and nmaB genes, which code for UDP-GlcNAc-2-epimerase and UDP-ManNAc-dehydrogenase, respectively, are involved in capsular polysaccharide biosynthesis in Mannheimia haemolytica A1. A chloramphenicol resistance (Cm(r)) cassette cloned behind an M. haemolytica A1 promoter, plpcat, was created and used to interrupt nmaA and nmaB. A 1.3-kbp DNA fragment that encompasses part of nmaA and nmaB was replaced by...

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Identifiers

PMID: 11953404
DOI: 10.1128/IAI.70.5.2622-2629.2002
PMCID: PMC127936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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