Article
[Genetics of human narcolepsy].
Revue neurologique - 1 Nov 2001
Dauvilliers Y, Tafti M, Billiard M
Abstract excerpt
Narcolepsy is known to be a complex disorder; both genetic and environmental factors play a role in its pathophysiology. Although narcolepsy presents one of the tightest association with a specific HLA antigen (DQB1*0602), there is strong evidence that non-HLA genes also confer susceptibility, both monoaminergic and hypocretinergic systems seem to be involved and may interfere with the phenotype. Implication of...
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