Article
Hepatitis C virus (HCV) RNA level determined by second-generation branched-DNA probe assay as predictor of response to interferon treatment in patients with chronic HCV viremia.
Digestive diseases and sciences - 1 Mar 2002
Furusyo Norihiro, Hayashi Jun, Kashiwagi Kenichiro, Nakashima Hisashi, Nabeshima Shigeki, Sawayama Yasunori, Kinukawa Naoko, Kashiwagi Seizaburo
Abstract excerpt
Using first- and second-generation branched-DNA probe assays (1st- and 2nd-bDNA), we investigated the predictors of favorable clinical response to interferon (IFN) treatment in patients with chronic HCV viremia. A total of 122 patients (85 genotype lb and 37 genotype 2a) with chronic HCV viremia received 24-week IFN-alpha treatment. Patients with sustained clearance of serum HCV RNA by polymerase chain reaction...
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