Article
The clinical spectrum of Bruton's agammaglobulinemia.
Current allergy and asthma reports - 1 Nov 2001
Stewart D M, Lian L, Nelson D L
Abstract excerpt
X-linked, or Bruton's, agammaglobulinemia (XLA) was described in 1952 as the congenital inability to form antibodies. Patients were typically infants or young children with recurrent, severe bacterial infections. Other, milder cases of hypogammaglobulinemia were considered "acquired," and often presented later in life. Since the discovery of the defective gene in XLA in 1993, it has been shown that a significant...
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