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Article

Rapidly progressive amyloid polyneuropathy associated with a novel variant transthyretin serine 25.

Muscle & nerve - 1 Feb 2002

Yazaki Masahide, Yamashita Taro, Kincaid John C, Scott John R, Auger Raymond G, Dyck Peter J, Benson Merrill D

Abstract excerpt

We report a 52-year-old woman with a novel transthyretin (TTR) variant serine replacing alanine at residue 25 [Ala25Ser (Serine 25)], who showed a unique clinical picture with a relatively acute onset neuropathy within a few days of an influenza vaccination, progressing to a severe degree within 2 years. Sural nerve biopsy revealed amyloid deposition in the endoneurium. Sequencing of the proband's DNA revealed a...

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Source

Identifiers

PMID: 11870693
DOI: 10.1002/mus.10032

Genes

TTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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