Article
Metabolomics and microarrays for improved understanding of phenotypic characteristics controlled by both genomics and environmental constraints.
Current opinion in biotechnology - 1 Feb 2002
Phelps Tommy J, Palumbo Anthony V, Beliaev Alex S
Abstract excerpt
Advances in our understanding of functional genomics are best addressed by integrative studies that include measurements of mRNA, proteins, and low molecular weight metabolites over time and varied conditions. Bioinformatics can then be used to relate this data to the genome. Current technology allows for comprehensive and rapid mRNA expression profiling and mass spectrophotometric measurement of low molecular...
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