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Article

Genetic analysis of PITX2 and FOXC1 in Rieger Syndrome patients from Brazil.

Journal of glaucoma - 1 Feb 2002

Borges Adriana Silva, Susanna Remo, Carani José Carlos Eudes, Betinjane Alberto J, Alward Wallace L, Stone Edwin M, Sheffield Val C, Nishimura Darryl Y

Abstract excerpt

PURPOSE: Axenfeld-Rieger syndrome is a genetically heterogeneous, autosomal dominant disorder that is characterized by anterior segment defects, glaucoma, and extraocular anomalies. This study examined the two genes known to cause Rieger syndrome, PITX2 and FOXC1, for mutations in five Brazilian families with Axenfeld-Rieger syndrome. METHODS: Five families with a total of 23 persons affected by Axenfeld-Rieger...

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Source

Identifiers

PMID: 11821690
DOI: 10.1097/00061198-200202000-00010

Genes

PITX2
FOXC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic analysis of PITX2 and FOXC1 in Rieger Syndrome patients from Brazil.PMID 11821690Read ↗

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