Article
Genetic variability within the species Leishmania infantum by RAPD. A lack of correlation with zymodeme structure.
Molecular and biochemical parasitology - 1 Feb 2002
Toledo Antonio, Martín-Sánchez Joaquina, Pesson Bernard, Sanchiz-Marín Cesarea, Morillas-Márquez Francisco
Abstract excerpt
The infraspecific variability of the species Leishmania infantum is studied by using genetic markers generated by random amplified polymorphic DNA (RAPD). We have applied this technique, using 18 primers of arbitrary sequence, to 33 strains of the parasite belonging to 18 zymodemes isolated in different clinical forms and hosts. Other strains belonging to the species L. donovani, L. major, L. tropica and L....
Topics
- Animals
- Enzyme Precursors
- Evolution, Molecular
- Genetic Markers
- Genetic Variation
- Leishmania infantum
- Leishmaniasis, Visceral
- Phylogeny
- Polymorphism, Genetic
- Random Amplified Polymorphic DNA Technique
- Reproducibility of Results
- Sensitivity and Specificity
- Spain