Article
Red cell genetic abnormalities, beta-globin gene haplotypes, and APOB polymorphism in the Great Andamanese, a primitive Negrito tribe of Andaman and Nicobar Islands, India.
Human biology - 1 Oct 2001
Murhekar K M, Murhekar M V, Mukherjee M B, Gorakshakar A C, Surve R, Wadia M, Phanasgaonkar S, Shridevi S, Colah R B, Mohanty D
Abstract excerpt
The Great Andamanese are a primitive Negrito tribe of the Andaman and Nicobar Islands, India, with a total population of 37. We studied 29 individuals from eight families from this population for abnormal hemoglobins, G6PD deficiency, DNA haplotypes, and apolipoprotein B (APOB, gene) polymorphism. Hb E was detected in five individuals, the prevalence of Hb E heterozygotes being 14.3%. One individual had...
Topics
- Adolescent
- Adult
- Apolipoproteins B
- Child
- Consanguinity
- Erythrocytes
- Female
- Gene Frequency
- Genetic Carrier Screening
- Genotype
- Geography
- Globins
- Glucosephosphate Dehydrogenase Deficiency