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Plasmid DNA Immunization against Japanese Encephalitis Virus:Immunogenicity of Membrane‐Anchored and Secretory Envelope Protein

1 Jan 2002

Abstract excerpt

Plasmid DNA synthesizing membrane-anchored or secretory Japanese encephalitis virus (JEV) envelope (E) protein and premembrane protein was delivered to mice by intramuscular injection or gene gun. Intramuscular plasmid immunization induced anti-E antibody responses similar to those associated with commercial JEV vaccine. The gene gun induced less antibody response. The 2 forms of the E protein induced similar...

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PMID: 11756975
DOI: 10.1086/338015

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