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Article

Rethinking the fate of males with mutations in the gene that causes Rett syndrome.

Brain & development - 1 Dec 2001

Schanen C

Abstract excerpt

Rett syndrome (RTT) is usually described as an X-linked dominant disorder that is lethal prenatally to males. While this hypothesis stemmed from the nearly exclusive recognition of the classical features in females and the scarcity of similarly affected or severely affected brothers of girls manifesting the classic phenotype, there are actually no pedigree data to support it. The identification of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11738861
DOI: 10.1016/s0387-7604(01)00340-0

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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