Article
Familial progressive supranuclear palsy: detection of subclinical cases using 18F-dopa and 18fluorodeoxyglucose positron emission tomography.
Archives of neurology - 1 Nov 2001
Piccini P, de Yebenez J, Lees A J, Ceravolo R, Turjanski N, Pramstaller P, Brooks D J
Abstract excerpt
BACKGROUND: Progressive supranuclear palsy (PSP) is generally considered to be a sporadic disease; however, occasional cases of familial PSP have been described. The rarity of reports of familial PSP may be attributed in part to an inability to detect subclinical disease in affected relatives who subsequently die before symptoms clinically develop. OBJECTIVE: To study regional cerebral dopaminergic function and...
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