Article
Polymorphism of the serotonin 5-HT1B receptor gene (HTR1B) associated with minimum lifetime body mass index in women with bulimia nervosa.
Biological psychiatry - 15 Oct 2001
Levitan R D, Kaplan A S, Masellis M, Basile V S, Walker M L, Lipson N, Siegel G I, Woodside D B, Macciardi F M, Kennedy S H, Kennedy J L
Abstract excerpt
BACKGROUND: Preclinical research has shown that the serotonin-1B receptor has important modulatory effects on feeding behavior and thus body weight. In the current study, we examined whether genetic variation of the serotonin-1B receptor was associated with minimum and maximum lifetime body mass indices (BMIs) in a sample of women with bulimia nervosa (BN). METHODS: Ninety-eight women with BN were genotyped based...
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