Article
Two signal transduction pathways involved in the catecholaminergic differentiation of avian neural crest-derived cells in vitro.
Molecular and cellular neurosciences - 1 Oct 2001
Wu X, Howard M J
Abstract excerpt
Molecules derived from the neural tube and found in chick embryo extract (CEE) and bone morphogenetic proteins (BMP) support the differentiation of neural crest-derived catecholaminergic (CA) neurons. We now report that intracellular signaling resulting in the activation of Map kinase (MapK) or translocation of Smad1 mediate the differentiation of CA neurons in response to CEE or BMP 4, respectively. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
