Article
Recombination events in Neurospora crassa may cross a translocation breakpoint by a template-switching mechanism.
Genetics - 1 Oct 2001
Yeadon P J, Rasmussen J P, Catcheside D E
Abstract excerpt
To assist investigation of the effect of sequence heterology on recombination in Neurospora crassa, we inserted the Herpes simplex thymidine kinase gene (TK) as an unselected marker on linkage group I, giving a gene order of Cen-his-3-TK-cog-lpl. We show here that in crosses heterozygous for TK, conversion of a his-3 allele on one homolog is accompanied by transfer of the heterologous sequence between cog and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
