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Article

Molecular analysis of CYP-21 mutations for congenital adrenal hyperplasia in Singapore.

Hormone research - 1 Jan 2001

Loke K Y, Lee Y S, Lee W W, Poh L K

Abstract excerpt

BACKGROUND: Congenital adrenal hyperplasia arising from 21-hydroxylase deficiency is associated with mutations in the CYP21 gene on chromosome 6p. This is the first report on the mutational spectrum of the CYP21 gene in Singapore. METHODS: To catalogue the mutations, ten exons of the CYP21 gene from 28 Singaporean patients were analyzed by PCR amplification and direct sequencing. RESULTS: Common mutations in...

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Share to Adrenal Hyperplasia, Congenital
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Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11598371
DOI: 10.1159/000049992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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