Article
DNA as a nutrient: novel role for bacterial competence gene homologs.
Journal of bacteriology - 1 Nov 2001
Finkel S E, Kolter R
Abstract excerpt
The uptake and stable maintenance of extracellular DNA, genetic transformation, is universally recognized as a major force in microbial evolution. We show here that extracellular DNA, both homospecific and heterospecific, can also serve as the sole source of carbon and energy supporting microbial growth. Mutants unable to consume DNA suffer a significant loss of fitness during stationary-phase competition. In...
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