Article
Nucleotide sequence and restriction fragment length polymorphisms of the equine Cvarepsilon gene.
Veterinary immunology and immunopathology - 1 Oct 2001
Wagner B, Siebenkotten G, Radbruch A, Leibold W
Abstract excerpt
IgE is the dominant immunoglobulin isotype involved in type I hypersensitivities in mammals. The heavy chain constant region domains of equine IgE are encoded by a single gene, the Cvarepsilon gene. By restriction analysis of cDNA from 15 unrelated horses, we have now identified two Cvarepsilon alleles, characterised by a Sma I restriction fragment length polymorphism, which we designated Cvarepsilon(a) and...
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